2011 Program Schedule

Wednesday, October 5, 2011

7:00 PM: Arrival and Registration

7:00 - 7:50 AM - Registration and Continental Breakfast

7:50 - 8:00 AM - Welcome and Opening - Norbert Leitinger, PhD

8:00 - 8:25 AM - Amanda Wibley Brown, PhD, Wake Forest University

• Alterations in monocyte subsets and monocyte trafficking by omega-3 fatty acids

8:25 - 8:50 AM - Ji-Young Lee, PhD, University of Connecticut

• Regulation of histone deacetylase expression by fatty acids

8:50 - 9:15 AM - Naima Moustaid-Moussa, PhD, University of Tennessee

• Dietary regulation of adipose tissue inflammation and insulin resistance

9:15 - 9:40 AM - Tahar Hajri, PhD, Vanderbilt University

• Very low density lipoprotein receptor and obesity-related metabolic abnormalities: another molecular determinant of insulin resistance and inflammation

9:40 AM - 10:15 AM - BREAK

10:15 - 10:40 AM - R. Daniel Rudic, Ph.D., Georgia Health Sciences University

• Circadian Clocks in the vascular system

10:40 - 11:05 AM - M. Mahmood Hussain, PhD, SUNY Downstate Medical Center

• Clocks and lipoprotein metabolism

11:05 - 11:30 PM - Molly S. Bray, PhD, University of Alabama, Birmingham

• Clocks and Adipose Function
  

11:30 - 11:55 PM - Elizabeth Schroder, PhD, University of Kentucky

• Cardiometabolic disease — the potential role of the molecular clock in skeletal muscle dysfunction

11:55 - 12:20 Martin E. Young, PhD, University of Alabama, Birmingham

• Clocks and myocardial metabolism

12:20 - 3:30 PM - LUNCH ON YOUR OWN - FREE TIME

3:30 - 5:00 PM - Special Educational Session: Graduate School to Post-Doc to “What Comes Next?" An Informal panel discussion with representatives from academia and industry highlighting career choices and the pro’s and con’s of each.

Moderator: Alyssa Hasty, PhD, Vanderbilt University
Panelists: Drs. Bruce Freeman, Ira Shulman, Lisa Cassis, John Parks, and Jay Wrobel

5:00 - 7:30 PM - POSTER SESSION and RECEPTION

8:00 - 8:15 - W Virgil Brown, M.D., Emory University

• History of the SELRC: 20th Anniversary Special

8:00 PM - 9:00 PM: W. VIRGIL BROWN KEYNOTE LECTURE

Bruce A. Freeman, PhD
Professor and Chair
Department of Pharmacology and Chemical Biology
University of Pittsburgh School of Medicine

Electrophilic fatty acid signaling mediators: new hammers in the redox toolbox

7:00 - 8:00 AM - Continental Breakfast

Session 3: Chemokines in Atherosclerosis and Diabetes
Moderator: Victoria L. King, PhD, University of Kentucky

8:00 - 8:20 AM - Nicki Baker, University of Kentucky

• The role of polychlorinated biphenyls in the development of diabetes

8:20 - 8:45 AM - Anca D. Dobrian, PhD, Eastern Virginia Medical School

• STAT4 deficiency reduces chemokine production and inflammation in adipose tissue

8:45 - 9:10 AM - Jeb S. Orr, PhD, Vanderbilt University

• CCR7 deficiency attenuates adipose tissue macrophage accumulation in obesity

9:10 - 9:35 AM - Nalini Santanam, PhD, Marshall University

• "Epicardial fat biomarkers from the West Virginia Appalachian Heart Study

9:35 - 10:00 - Lisa A. Cassis, PhD, University of Kentucky

• Role of the adipocyte renin-angiotensin system in metabolic syndrome

10:00 AM - 10:30 AM - BREAK

10:30 - 10:50 AM - Timo D. Mueller, PhD, University of Cincinnati

• Sequestosome 1 Controls Energy Expenditure

10:50 - 11:10 AM - Dennis Bruemmer, MD, PhD, University of Kentucky

• Telomeres in metabolism and inflammation

11:10 - 11:30 PM - Soonkyu Chung, PhD, University of Florida

• Establishment of primary human brown adipocyte cultures from adipogenic stem cells

11:20 - 11:50 - Marissa Smith, PhD, University of Virginia

• Mi-2b and lipin mediate adipogenesis and inflammatory gene transcription

11:50 - 5:00 PM - LUNCH AND FREE TIME

5:00 - 5:25 PM - Keith D. Baker, PhD, Virginia Commonwealth University

• Metabolic transitions orchestrated by Drosophila ERR

5:25 - 5:50 PM - Sayeepriyadarshini Anakk, PhD, Baylor College of Medicine

• FXR & SHP double knockouts – bitter, bigger, and leaner

5:50 - 6:15 PM - Ira G. Schulman, PhD, University of Virginia

• Regulation of reverse cholesterol transport and atherosclerosis by LXRs

6:15 - 6:40 PM - Jay Wrobel, PhD, Fox Chase Chemical Diversity Center

• New generation of LXR modulators. Lessons learned from WAY-25263
  

6:40 PM - DINNER ON YOUR OWN

7:00 - 8:00 AM - Continental Breakfast

Session 6: Clinical Aspects of Atherosclerosis and Diabetes
Moderator: Coleen McNamara, MD, University of Virginia

8:00 - 8:25 AM - Peter Wilson, MD, Emory University

• Overview of atherosclerosis and diabetes

8:25 - 8:50 AM - Lisa Tannock, MD, University of Kentucky

• Inflammation in T2DM: risk marker or risk factor?

8:50 - 9:15 AM - Angela Taylor, MD, University of Virginia

• Structural and functional biomarkers of atherosclerosis in humans

9:15 - 9:40 AM - Mark C. Kowala, PhD, Eli Lilly

• Challenges of translating basic findings to the clinical arena

9:40 - 10:00 AM - Panel Discussion

• Translating basic findings to the clinic

10:00 AM - 10:30 AM - BREAK

10:30 - 10:45 AM - Jason Meyer, University of Kentucky

• Selective cholesteryl ester uptake from native LDL contributes to macrophage foam cell formation

10:45 - 11:00 PM - Brian E. Cox, PhD, Vanderbilt University

• The effects of cholesterol, triglycerides, and fatty acids on lysosomal function

11:00 - 11:25 - Sean S. Davies, PhD, Vanderbilt University

• Lipid aldehydes induce inflammation by modifying phosphatidylethanolamine

11:25 - 11:40 PM - Caleb Lord, Wake Forest University

• CGI-58/Abhd5 regulates macrophage content in adipose tissue

11:40 - 12:05 PM - Kyle L. Hoehn, PhD, University of Virginia

• The role of ceramide and mitochondrial ROS in insulin resistance

12:05 - 12:30 PM - Nicholas Khoo, PhD, University of Pittsburgh

• New therapeutic strategies for obesity-induced type 2 diabetes using electrophilic nitro-fatty acids.

12:30 PM: Closing Comments and Adjournment - Norbert Leitinger and Alyssa Hasty