Conference Chair:Gregory S. Graf, PhD, University of Kentucky
Vice Chair: Kasey C. Vickers, MD, Vanderbilt University

2015 Preliminary Program Schedule

Wednesday, September 16, 2015

7:00 PM: Arrival and Registration


Thursday, September 17, 2014

7:00 – 7:50 AM: Registration and Continental Breakfast

7:50 – 8:00 AM: Welcome and Opening — Gregory Graf, PhD


Session 1: HDL Structure/Composition and Function
Moderator: John Parks, Wake Forest University

8:00 – 8:30 AM: Allison Weckerle, Wake Forest

  • Is apoL1 really an HDL apolipoprotein?

8:30 – 9:00 AM: Ryan Temel, University of Kentucky

  • Impact of hepatic NPC1L1 and ABCG5/G8 on atherosclerosis and RCT

9:00 – 9:30 AM: Sean Davidson, University of Cincinnati

  • The influence of HDL structure on its function

9:30 – 10:00 AM: John Stafford, Vanderbilt University

  • Liver pathways that influence HDL composition and function in obesity

10:00 AM – 10:30 AM: BREAK


Session 2: Noncoding RNAs in Physiologoy and Therapeutics
Moderator: TBD

10:30 – 11:00 AM: Kasey C. Vickers, Vanderbilt University

  • Lipoprotein transport of small RNAs in Familial Hypercholesterolemia

11:00 – 11:30 AM: Daping Fan, University of South Carolina, School of Medicine

  • The Role of miR-155 in atherogenesis and beyond

11:30 – 12:00 PM: Bailey Peck, graduate student, University of North Carolina at Chapel Hill

  • Investigating microRNA Regulatory Networks in the Intestinal Epithelium

12:00 – 12:30 PM: Jonathan Haldeman, Duke University School of Medicine

  • The function and regulation of the miR-17~92 cluster in the pancreatic beta-cell

12:30 – 5:30 PM: Free Time Early Career Programming - Trainee Networking Social Hours

5:30 – 7:30 PM: POSTER SESSION and RECEPTION


8:00 PM – 9:00 PM: W. VIRGIL BROWN KEYNOTE LECTURE

Dietary Fatty Acids and the Metabolic Syndrome

Nada Abumrad, PhD

Robert C. Atkins Professor of Obesity Research in Medicine
Washington University School of Medicine in St. Louis


Friday, September 18, 2015

7:00 – 8:00 AM: Continental Breakfast

Session 3: Macrophages and the Microenvironment
Moderator: Lisa Makowski, (Chair, UNC)

8:00 – 8:30 AM: Norbert Leitinger, PhD, University of Virginia

  • Metabolism and inflammatory state of adipose tissue macrophages

8:30 – 9:00 AM: Bill Zamboni, University of North Carolina

  • Bi-directional interaction between mononuclear phagocyte system and liposomal and carrier-mediated agents in preclinical models and patients

9:00 – 9:30 AM: Alyssa Hasty, PhD, Vanderbilt University

  • A novel role for adipose tissue macrophages in iron metabolism

9:30 – 10:00 AM: TBD

10:00 AM – 10:30 AM: BREAK


Session 4: Emerging Therapies in Clinical Cardiology
Moderator: Virgil Brown, Emory University

10:30 – 11:00 AM: James Revkin, Pfizer, Inc.

  • Clinical trial results with PCSK9 mAbs

11:00 – 11:30 AM: Chip Davis, CVPath Institute

  • The long and winding road of Ezetimibe

11:30 – 12:00 PM: Chip Davis, CVPath Institute

  • The improve-IT trial

12:00 – 12:30 PM: Virgil Brown, Emory University

  • ApoCIII as a developing risk factor for vascular disease

12:30 – 3:30 PM: LUNCH & FREE TIME

3:30 – 5:00 PM: CHALK TALKS FOR POST-DOCTORAL FELLOWS (light refreshments provided)


Session 5: Computational Applications in Cardiometabolic Disease
Moderator: Alison Motsinger-Reif, North Carolina State University

5:30 – 6:00 PM: Alison Motsinger-Reif, North Carolina State University

  • Topic TBA

6:00 – 6:30 PM: Stella Aslibekyen, University of Alabama, Birmingham

  • Topic TBA

6:30 – 7:00 PM: TBA

7:00 – 7:30 PM: TBA

7:30 PM: DINNER ON YOUR OWN


Saturday, September 19, 2015

7:00 - 8:00 AM: Continental Breakfast

Session 6:   Bile Acids, Physiology to Therapeutics
Moderator: Paul Dawson, Emory University

8:00 – 8:30 AM:Saul Karpen, Emory University

  • Bile acids and fatty liver

8:30 – 9:00 AM: Grace Guo, Rutgers University

  • FXR signaling

9:00 – 9:30 AM: Phil Hylemon, Virginia Commonwealth University

  • Bile acid signaling in the liver

9:30 – 10:00 AM: TBA

10:00 – 10:30 AM: BREAK

Session 7: Regulation of Lipogenesis and Fatty Acid Oxidation
Moderator: Edwards Park, (Chair, University of Tennessee Health Sciences Center)

10:30 – 11:00 AM: Randall Mynatt, Louisiana State University, Pennington

  • Impaired mitochondrial fat oxidation induces adaptive remodeling of muscle metabolism

11:00 – 11:30 AM: Dave Bridges, University of Tennessee Health Sciences Center

  • mTORC and insulin signaling

11:30 – 12:00 AM: Thurl Harris, University of Virginia

  • Adipocyte insulin resistance induced by the acute stress response

12:00 – 12:30 PM: Marshall Elam, University of Tennessee Health Sciences Center

  • Kinase pathways mediating activation of SREBP-1c and hepatic lipid synthesis


12:30 PM: Closing Comments and Adjournment Gregory Graf and Kasey Vickers